Urgent Updates | July 21, 2022 

ANALYSIS OF COVID-19–RELATED CROUP AND SARS-COV-2 VARIANT PREDOMINANCE IN THE USThis cross-sectional study included children aged 3 months to 8 years with diagnoses of COVID-19 and croup between January 1, 2021, and March 26, 2022, using data from 43 US children’s hospitals in the Pediatric Health Information System. Researchers identified 5152 children with COVID-19–related croup (3329 [64.6%]

Urgent Updates | July 14, 2022 

PHYSICIANS REACT: COMPENSATION ISN’T WORTH THE HASSLES. WHAT’S THE SOLUTION?Medscape’s Physician Compensation Report 2022: “Incomes Gain, Pay Gaps Remain” generally shows encouraging trends. And for the first time in Medscape’s 11 years of reporting on physician compensation, average income rose for every medical specialty surveyed. Many commenters were highly distressed or even angry about their

Urgent Updates | July 7, 2022 

A MULTISITE COLLABORATIVE TO DECREASE INAPPROPRIATE ANTIBIOTICS IN URGENT CARE CENTERSThe Society of Pediatric Urgent Care invited pediatric UC clinicians to participate in a multisite quality improvement study from June 2019 to December 2019. The diagnoses included acute otitis media (AOM), otitis media with effusion, and pharyngitis. Algorithms based on published guidelines were used to

Urgent Updates | June 30, 2022 

COMPARISON OF HOME ANTIGEN TESTING WITH RT-PCR AND VIRAL CULTURE DURING THE COURSE OF SARS-COV-2 INFECTIONIn this prospective cohort study of 225 adults and children with reverse transcription–polymerase chain reaction (RT-PCR)–confirmed SARS-CoV-2 infection, antigen test sensitivity was 64% and 84% when compared with same-day RT-PCR and viral culture, respectively. The study results suggest that symptomatic

Urgent Updates | June 23, 2022

ANALYSIS OF RACIAL AND ETHNIC DIVERSITY OF POPULATION SERVED AND IMAGING USED IN US CHILDREN’S HOSPITAL EMERGENCY DEPARTMENTSIn this cross-sectional study of 38 children’s hospitals encompassing more than 12 million ED visits, hospitals with a higher percentage of patients from minoritized groups had larger differences in imaging between non-Hispanic Black and non-Hispanic White patients, with

Urgent Updates | June 16, 2022

FROM POSITIVE TO NEGATIVE TO POSITIVE AGAIN—THE MYSTERY OF WHY COVID-19 REBOUNDS IN SOME PATIENTS WHO TAKE PAXLOVIDScientists have proposed possible explanations for rebounds after nirmatrelvir/ritonavir treatment. Timing – maybe medication is started too early in the disease. Perhaps If you get started right away, maybe you suppress the virus, and the immune system doesn’t

Urgent Updates | June 9, 2022

LIDOCAINE INFUSIONS FOR REFRACTORY CHRONIC MIGRAINE: A RETROSPECTIVE ANALYSISPatients with refractory chronic migraine have poor quality of life. Intravenous infusions are indicated to rapidly ‘break the cycle’ of pain. The records of 832 hospital admissions involving continuous multiday lidocaine infusions for migraine were reviewed. In total, 609 patient admissions met criteria for refractory chronic migraine. Median pain

Urgent Updates | June 3, 2022

A NOVEL INTERNATIONAL MONKEYPOX OUTBREAKA new, unusual, multinational outbreak of monkeypox that is unfolding rapidly makes it important to know what a case might look like. Clinicians seeing patients with new onset of febrile illness and rash should consider monkeypox, especially if lymphadenopathy is also present. The rash typically starts in the mouth, then moves

Urgent Updates | May 26, 2022

HOW REPEATED INFLUENZA VACCINATION EFFECTS MIGHT APPLY TO COVID-19 VACCINES If repeated COVID-19 vaccination leads to blunted vaccine effectiveness or a reduction in protection relative to people who are unvaccinated, findings from new studies comparing different influenza vaccine types and vaccine strategies point to at least four lessons to be learned including, vaccine effectiveness studies

Urgent Updates | May 20, 2022

MORE ON RELAPSES AFTER PAXLOVID TREATMENT FOR COVID-19Some people treated for COVID-19 with Paxlovid experience a relapse in illness shortly after stopping treatment – a recurrence of symptoms and a positive antigen test – sometimes after the test became negative. Relapses vary in severity, from very mild and brief to worse than the initial illness. Pfizer