URGENT UPDATES | SEPTEMBER 1, 2022 

ROCHE GETS U.S. APPROVAL FOR FLU DRUG FOR CHILDREN AGED 5 AND OVER
U.S. Food and Drugs Administration approved Xofluza drug to treat influenza in children aged five years and older. The medicine has been approved to treat acute uncomplicated influenza in otherwise healthy children who have shown symptoms for no more than 48 hours. The FDA also approved Xofluza to prevent influenza in children aged five years and above following contact with an infected person.
Full Access: Reuters 

OUTCOMES IN PATIENTS WITH MILD TRAUMATIC BRAIN INJURY WITHOUT ACUTE INTRACRANIAL TRAUMATIC INJURY
 In this cohort study of 991 participants with TBI with GCS score of 15 and negative head CT scan, 27% had functional recovery and 73% had incomplete recovery 2 weeks after the injury. At 6 months after the injury, 44% had functional recovery and 56% had incomplete recovery. Findings suggest that clinicians should recommend a 2-week follow-up for patients with TBI, a GCS score of 15, and a negative head CT scan to identify those with incomplete recovery and to facilitate their rehabilitation.
Full Access: JAMA

CLINICIANS’ RELUCTANCE TO DISCUSS POSSIBLE HARMS IS LETTING DOWN A GENERATION OF WOMEN
Two researchers from the United Kingdom wrote an opinion article published in The BMJ. Clinicians’ reluctance to discuss possible harms of anal sex may be letting down a generation of young women who are unaware of the risks. Asking about anal sex is standard practice in genitourinary medicine clinics because of its association with alcohol, drug use, and multiple sex partners, anal intercourse is considered a risky sexual behavior.
Full Access: BMJ

REMOVING RACE COEFFICIENT FROM EGFR EQUATION CHANGES CKD STAGE FOR 28% OF BLACK PATIENTS
When the race coefficient was removed from the eGFR equation, 28.1% of Black patients were reclassified to a more severe chronic kidney disease stage. Researchers examined 80,090 serum creatinine values from 56,676 adults (31.4% were Black; 67.5% were women). Data were derived from electronic medical records during a 16-month period. Once researchers removed the race coefficient from the equation, 28.1% of Black patients were reclassified to a more severe CKD stage; 39% of these patients were reclassified from stage 3A CKD to stage 3B CKD.
Full Access: Helio